CLFS Subject to Reasonable Charge Payment: October 2025 Update

Related CR Release Date: September 5, 2025
MLN Matters Number: MM14211
Effective Date: October 1, 2025 
Related Change Request (CR) Number: CR 14211
Implementation Date: October 6, 2025 
Related CR Transmittal Number: R13362CP 

CR 14211 tells you about:

  • When the next Clinical Laboratory Fee Schedule (CLFS) reporting period for clinical diagnostic laboratory tests (CDLTs) begins
  • New and deleted CPT codes effective October 1, 2025

Make sure your billing staff know about these changes.

View the complete CMS Medicare Learning Network (MLN) Matters (MM)14211.

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