Article Detail - JF Part B
Billing and Coding: MolDX: Minimal Residual Disease Testing for Solid Tumor Cancers (A58456) - R15 - Effective Multiple Dates, 2025
Date Posted: December 18, 2025
This Billing and Coding Article has been revised under contract numbers: 02102 (AK), 02202 (ID), 02302 (OR), 02402 (WA), 03102 (AZ), 03202 (MT), 03302 (ND), 03402 (SD), 03502 (UT), and 03602 (WY).
Effective Date: Multiple Dates, 2025
Summary of Changes:
Under Article Text revised Table 1 row 11 to read "NavDx". Under subheading Additional Test-specific Indications, Limitations and Instructions revised 2nd sentence to add "cancer". Revised "NavDX" to read "NavDx". Formatting was corrected throughout the article. This revision is effective 12/18/2025.
Under Article Text revised Table 1 row 9 to add "NeXT Personal Dx Breast MRD Recurrence Monitoring Test: WGS Assay Design + Plasma Initial Test (Personalis, Inc)". Revised row 10 to add "NeXT Personal Single Plasma Test (Personalis, Inc)". Under subheading Additional Test-specific Indications, Limitations and Instructions revised 2nd sentence to add "NeXT Personal". This revision is due to a new covered test that has successfully completed a TA and is effective for 10/7/2025.
Under subheading Additional Test-specific Indications, Limitations and Instructions revised 2nd sentence to add "and anal squamous cell". Under ICD-10 Codes that Support Medical Necessity Group 3: Codes added Z85.048. This revision is due a new covered test that has successfully completed a TA and is effective for 1/8/2025.
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