2026 Annual Quarter One MolDX CPT/HCPCS Billing and Coding Article Updates - Effective January 1, 2026

Date Posted: January 22, 2026

The following MolDX Billing and Coding Articles have been revised under contract numbers: 01111 (CA), 01211 (AS, GU, HI, NMI), 01311 (NV), and 01911 (CA, HI & Territories).

Effective Date: January 1, 2026

Summary of Changes: The following MolDX Billing and Coding Articles have been updated to include and/or remove CPT/HCPCS codes as well as update descriptions. For description changes, either the short and/or long code description was changed. Please Note: Depending on which descriptor was used, there may not be any changes to the code display in the article.

MCD Number Billing and Coding Article Title New CPT/HCPCS Codes Deleted CPT/HCPCS Codes CPT/HCPCS Codes Descriptor changes
A59641 Billing and Coding: MolDX: Proteomics Testing 0601U, 0609U 0550U 0365U
A57331 Billing and Coding: MolDX: Repeat Germline Testing 0605U, 81354 0033U, 0131U, 0132U, 0135U NA
A58168 Billing and Coding: MolDX: Molecular Testing for Solid Organ Allograft NA 0508U, 0509U, 0544U NA

Visit the Active MolDX Billing and Coding Articles webpage or the Active MolDX LCD webpage to view the Billing and Coding Article or access it via the CMS Medicare Coverage Database (MCD).

Last Updated Jan 21 , 2026