The Molecular Diagnostic Services (MolDX) Program was developed by Palmetto GBA in 2011 to identify and establish coverage and reimbursement for molecular diagnostic tests. This program performs the following functions.

• Facilitates detailed and unique identification through registration of molecular diagnostic tests to facilitate claims processing and to track utilization.
• Establishes clinical utility expectations.
• Completes technical assessments of published test data to determine clinical utility and coverage.
• Establishes reimbursement.

View the MolDX Molecular Test Registration and Claims Submission [PDF]

View the MolDX: Molecular Test Registration Requirement for Hospital Laboratories [PDF]

View the Molecular Diagnostic Program (MolDX®) Manual [PDF]

Palmetto GBA currently administers the MolDX Program and all its information.

Active LCDs - View all active Local Coverage Determinations (LCDs)

Covered Tests - View MolDX LCDs and LCD Articles

Excluded Tests - View MolDx tests excluded from coverage

Proposed LCDs - View all proposed LCDs

Claim Submission Reminders

• Submit only one Z-code per CPT that requires one
• Submit Z-code in Loop 2400/SV101-7
• If no Z-code is submitted, CPT will deny
• Do not submit any other characters or test names. Doing so will slow claims processing and possibly cause incorrect denials

Responsibilities