Number: 14477 
Release Date: June 16, 2026
Effective Date: July 1, 2026 
Implementation Date: July 6, 2026
Transmittal Number: R13832CP

CR 14477 tells you about:

• New COVID-19 monoclonal antibody products and administration codes
• CPT proprietary laboratory analyses (PLA) coding changes
• New and reassigned Category III CPT codes
• Device pass-through and device offset information
• Ambulatory payment classification (APC) assignment and status indicator changes
• Drugs, biologicals, and radiopharmaceuticals
• Non-opioid treatments for pain relief
• Skin substitute products

Make sure your billing staff knows about these Hospital Outpatient Prospective Patient System (OPPS) updates, effective July 1, 2026.

View the complete CMS Medicare Learning Network (MLN) Matters (MM)14477.