Policy Revision(s) for Multiple MolDX Billing and Coding Articles - Effective February 19, 2026

Date Posted: February 19, 2026

The following Billing and Coding Articles have been retired under contractor numbers: 02101 (AK), 02201 (ID), 02301 (OR), 02401 (WA), 03101 (AZ), 03201 (MT), 03301 (ND), 03401 (SD), 03501 (UT), and 03601 (WY).

Medicare Coverage Database Number Billing and Coding Article Title New Medicare Coverage Database Number
A55712 Billing and Coding: MolDX: Abbott RealTime IDH1 and IDH2 testing for Acute Myeloid Leukemia (AML) A55711
A54976 Billing and Coding: MolDX: Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) Testing A54975
A55600 Billing and Coding: MolDX: BCR-ABL A55595
A54388 Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID® Update A54386
A55116 Billing and Coding: MolDX: BluePrint® Test A55115
A54420 Billing and Coding: MolDX: FDA-Approved BRAF Tests A54418
A54424 Billing and Coding: MolDX: FDA-Approved EGFR Tests A54422
A59642 Billing and Coding: MolDX: Proteomics Testing A59641
A54500 Billing and Coding: MolDX: FDA-Approved KRAS Tests A54498
A55295 Billing and Coding: MolDX: Germline testing for use of PARP inhibitors A54422
A57972 Billing and Coding: MolDX: HLA Testing for Transplant Histocompatibility A57970
A55265 Billing and Coding: MolDX: HTTLPR Gene Testing A55264
A54447 Billing and Coding: MolDX: MammaPrint A54445
A56104 Billing and Coding: MolDX: Microsatellite Instability-High (MSI-H) and Mismatch Repair Deficient (dMMR) Biomarker for Patients with Unresectable or Metastatic Solid Tumors A56103
A54482 Billing and Coding: MolDX: Oncotype DX® Breast Cancer Assay A54480
A54486 Billing and Coding: MolDX: Oncotype DX® Colon Cancer A54484
A55602 Billing and Coding: MolDX: PIK3CA Gene Tests A55597
A55628 Billing and Coding: MolDX: SEPT9 Gene Test A55623
A57843 Billing and Coding: MolDX: Short Tandem Repeat (STR) Markers and Chimerism (CPT® codes 81265-81268) A57842
A55601 Billing and Coding: MolDX: SULT4A1 Genetic Testing A55596
A56518 Billing and Coding: MolDX: Targeted and Comprehensive Genomic Profile Testing in Cancer A55624
A58121 Billing and Coding: MolDX: Testing of Multiple Genes A58120
A58674 MolDX: Algorithm definition as a component of a laboratory test A58673
A59744 MolDX: Clarification of Order Requirements for Laboratory and Molecular Diagnostic services A59743
A59687 MolDX: Defining panel services in MolDX A59685

Effective Date: February 19, 2026

Rationale: The above-mentioned Billing and Coding Articles were retired to consolidate JF policies with JE policies to have one unified document and policy number. Per the Centers for Medicare & Medicaid Services (CMS), this update is considered non-substantive and does not alter the intent of coverage or non-coverage outlined in any article.

Visit the CMS Medicare Coverage Database (MCD) to access the Retired articles.

Last Updated Feb 19 , 2026