Active MolDX Billing and Coding Articles and Educational Articles

All LCDs are the same for each state within a Jurisdiction and are accessible from the table below.

Access LCD or Article: Select the LCD or Article number in the table below to view the policy or article on the Medicare Coverage Database (MCD).

Print the LCD or Article: Select the LCD or Article number in the table below to view the policy or article on the Medicare Coverage Database (MCD).

  1. Click on the blue download arrow on the right side of page when LCD or Article appears.
  2. Click the print when PDF opens.

Once you access the LCD, the "Coding Guidelines" can be found under the heading, "LCD Attachments" near the end of the document. Note: All CPT/HCPCS codes listed are mentioned in the LCD, but are not necessarily subject to diagnosis codes or coverage criteria.

 
Topic Article Number CPT/HCPCS Codes Referenced
Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID® A54388 81540
Billing and Coding: MolDX: BluePrint® A55116 81479
Billing and Coding: MolDX: FDA-Approved BRAF Tests A54420 81210
Billing and Coding: MolDX: HLA Testing for Transplant Histocompatibility A57972 81370, 81371, 81372, 81373, 81375, 81376, 81378, 81379, 81380, 81382
Billing and Coding: MolDX: HTTLPR Gene Testing A55265 81479
Billing and Coding: MolDX: PIK3CA Gene Tests A55602 81309, 0155U
Billing and Coding: MolDX: Prometheus® IBD sgi Diagnostic® Policy A57517 81479
Billing and Coding: MolDX: Proteomics Testing A59642 81490, 81500, 81503, 81517, 81538, 81539, 81599, 0002M, 0003M, 0015M, 0019M, 0002U, 0003U, 0021U, 0080U, 0092U, 0095U, 0105U, 0117U, 0166U, 0174U, 0206U, 0207U, 0228U, 0247U, 0249U, 0259U, 0263U, 0295U, 0308U, 0309U, 0310U, 0312U, 0322U, 0344U, 0351U, 0360U, 0365U, 0366U, 0367U, 0375U, 0384U, 0385U, 0387U, 0407U, 0412U, 0415U, 0436U, 0446U, 0447U, 0458U, 0468U, 0503U, 0541U, 0568U, 0573U 0577U, 0579U, 0591U, 0599U, 0601U, 0609U
Billing and Coding: MolDX: SEPT9 Gene Test A55628 81327
Billing and Coding: MolDX: Short Tandem Repeat (STR) Markers and Chimerism (CPT® codes 81265-81268) A57843 81265, 81266, 81267, 81268
Billing and Coding: MolDX: SULT4A1 Genetic Testing A55601 81479
Billing and Coding: MolDX: Targeted and Comprehensive Genomic Profile Testing in Cancer A56518 N/A
Billing and Coding: MolDX: Testing of Multiple Genes A58121 N/A
MolDX: Algorithm definition as a component of a laboratory test A58674 N/A
MolDX: Clarification of Order Requirements for Laboratory and Molecular Diagnostic Services A59744 NA
MolDX: Defining panel services in MolDX A59687 N/A
Last Updated Jan 22 , 2026