2025 HCPCS Code Update - July Edition - Correct Coding

Joint DME MAC and PDAC Publication
Posted June 26, 2025

The following tables identify changes to Level II Healthcare Common Procedure Coding System (HCPCS) codes for July 2025. The tables contain only HCPCS codes applicable to items within Medicare DME MAC jurisdiction. There may be other HCPCS code changes for items under the jurisdiction of other Medicare contractors. Consult those contractors for information regarding HCPCS codes within their areas of responsibility.

All HCPCS code changes are effective for claims with dates of service on or after July 1, 2025.

Code Change Categories

  • Added Codes/Modifiers: Identifies newly created codes and modifiers. Listing of a code in the tables does not necessarily indicate coverage. Refer to the applicable Local Coverage Determination for information regarding Medicare reimbursement requirements.
  • Discontinued Codes/Deleted Modifiers: Identifies codes and modifiers discontinued or deleted in the new cycle. These codes and modifiers continue to be valid for Medicare claims with dates of service either on or before June 30, 2025. There is no grace period for submission of a discontinued code/modifier for claims with dates of service after its effective end date. If there is a direct crosswalk for a discontinued/deleted code or modifier, the crosswalk code will be displayed in a table.
  • Narrative Changes: Identifies changes in the narrative descriptor for an existing code or modifier.

Added Codes

External Infusion Pumps

Code Narrative
J7356 INJECTION, FOSCARBIDOPA 0.25 MG/FOSLEVODOPA 5 MG

Miscellaneous

Code Narrative
J0165 INJECTION, EPINEPHRINE, NOT OTHERWISE SPECIFIED, 0.1 MG
J0166 INJECTION, EPINEPHRINE (BPI), NOT THERAPEUTICALLY EQUIVALENT TO J0165, 0.1 MG
J0167 INJECTION, EPINEPHRINE (HOSPIRA), NOT THERAPEUTICALLY EQUIVALENT TO J0165, 0.1 MG
J0168 INJECTION, EPINEPHRINE (INTERNATIONAL MEDICATION SYSTEMS), NOT THERAPEUTICALLY EQUIVALENT TO J0165, 0.1MG
J0169 INJECTION, EPINEPHRINE (ADRENALIN), NOT THERAPEUTICALLY EQUIVALENT TO J0165, 0.1 MG
J0618 INJECTION, CALCIUM CHLORIDE, 2 MG
J1163 INJECTION, DILTIAZEM HYDROCHLORIDE, 0.5 MG
J1326 INJECTION, ZOLBETUXIMAB-CLZB, 2 MG
J2312 INJECTION, NALOXONE HYDROCHLORIDE, NOT OTHERWISE SPECIFIED, 0.01 MG
J2313 INJECTION, NALOXONE HYDROCHLORIDE (ZIMHI), 0.01 MG
J3373 INJECTION, VANCOMYCIN HYDROCHLORIDE, 10 MG
J3374 INJECTION, VANCOMYCIN HYDROCHLORIDE (MYLAN), NOT THERAPEUTICALLY EQUIVALENT TO J3373, 10 MG
J3375 INJECTION, VANCOMYCIN HYDROCHLORIDE (XELLIA), NOT THERAPEUTICALLY EQUIVALENT TO J3373, 10 MG
J3391 INJECTION, ATIDARSAGENE AUTOTEMCEL, PER TREATMENT
J7172 INJECTION, MARSTACIMAB-HNCQ, 0.5 MG
J9174 INJECTION, DOCETAXEL (BEIZRAY), 1 MG
J9220 INJECTION, INDIGOTINDISULFONATE SODIUM, 1 MG
J9275 INJECTION, COSIBELIMAB-IPDL, 2 MG
J9276 INJECTION, ZANIDATAMAB-HRII, 2 MG
J9289 INJECTION, NIVOLUMAB, 2 MG AND HYALURONIDASE-NVHY
J9341 INJECTION, THIOTEPA (TEPYLUTE), 1 MG
J9342 INJECTION, THIOTEPA, NOT OTHERWISE SPECIFIED, 1 MG
J9382 INJECTION, ZENOCUTUZUMAB-ZBCO, 1 MG
Q2058 OBECABTAGENE AUTOLEUCEL, 10 UP TO 400 MILLION CD19 CAR-POSITIVE VIABLE T CELLS, INCLUDING LEUKAPHARESIS AND DOSE PREPARATION PROCEDURES, PER INFUSION

Discontinued Codes

Miscellaneous

Code Narrative
J0171 INJECTION, ADRENALIN, EPINEPHRINE, 0.1 MG
J0173 INJECTION, EPINEPHRINE (BELCHERR), NOT THERAPEUTICALLY EQUIVALENT TO J0171, 0.1 MG
J2310 INJECTION, NALOXONE HYDROCHLORIDE, PER 1 MG
J2311 INJECTION, NALOXONE HYDROCHLORIDE (ZIMHI), 1 MG
J3370 INJECTION, VANCOMYCIN HCL, 500 MG
J3371 INJECTION, VANCOMYCIN HCL (MYLAN), NOT THERAPEUTICALLY EQUIVALENT TO J3370, 500 MG
J3372 INJECTION, VANCOMYCIN HCL (XELLIA), NOT THERAPEUTICALLY EQUIVALENT TO J3370, 500 MG
J9340 INJECTION, THIOTEPA, 15 MG

Narrative Changes

Miscellaneous

Code Old Narrative New Narrative
J1954 INJECTION, LEUPROLIDE ACETATE FOR DEPOT SUSPENSION (CIPLA), 7.5 MG INJECTION, LEUPROLIDE ACETATE FOR DEPOT SUSPENSION (LUTRATE DEPOT), 7.5 MG
J9292 INJECTION, PEMETREXED (AVYXA), NOT THERAPEUTICALLY EQUIVALENT TO J9035, 10 MG INJECTION, PEMETREXED DIPOTASSIUM, 10 MG

For questions about correct coding or products not listed on the DMECS Product Classification List (PCL), contact the Pricing, Data Analysis and Coding (PDAC) HCPCS Helpline at (877) 735-1326 during the hours of 9:30 a.m. to 5:00 p.m. ET, Monday through Friday. You may also visit the PDAC website to chat with a representative or select the Contact Us button at the top of the PDAC website for email, FAX, or postal mail information.

Publication History

Date of Change Description
06/26/25 Originally published
Last Updated Jun 26 , 2025