2025 MolDX CPT/HCPCS Billing and Coding Article Updates - Effective January 1, 2025

Date Posted: January 9, 2025

The following MolDX Billing and Coding Articles have been revised under contractor numbers: 02101 (AK), 02201 (ID), 02301 (OR), 02401 (WA), 03101 (AZ), 03201 (MT), 03301 (ND), 03401 (SD), 03501 (UT), and 03601 (WY).

Effective Date: January 1, 2025

Summary of Changes: The following MolDX Billing and Coding Articles have been updated to include and/or remove CPT/HCPCS codes as well as update descriptions. For description changes, either the short and/or long code description was changed. Please Note: Depending on which descriptor was used, there may not be any changes to the code display in the article.

MCD Number Billing and Coding Article Title New CPT/HCPCS Codes Deleted CPT/HCPCS Codes CPT/HCPCS Codes Descriptor changes
A59522 Billing and Coding: MolDX: Molecular Biomarker Testing to Guide Targeted Therapy Selection in Rheumatoid Arthritis N/A 0456U N/A
A59642 Billing and Coding: MolDX: Proteomics Testing 0247U N/A 0095U, 0365U, 0468U
A57332 Billing and Coding: MolDX: Repeat Germline Testing 0529U 81433, 81436, 81438, 0380U 81432, 81434, 81435, 81437
A57385 Billing and Coding: MolDX: Pharmacogenomics Testing N/A 0380U N/A
A58170 Billing and Coding: MolDX: Molecular Testing for Solid Organ Allograft Rejection 81558 N/A N/A
A58681 Billing and Coding: MolDX: Lab-Developed Tests for Inherited Cancer Syndromes in Patients with Cancer N/A 81433, 81436, 81438 81432, 81435, 81437

Visit the Active MolDX Billing and Coding Articles webpage or the Active MolDX LCD webpage to view the Billing and Coding Article or access it via the CMS Medicare Coverage Database (MCD).

Last Updated Jan 09 , 2025