CLFS 2026 Annual Update

Related CR Release Date: December 5, 2025
MLN Matters Number: MM14312
Effective Date: January 1, 2026 
Related Change Request (CR) Number: CR 14312
Implementation Date: January 5, 2026 
Related CR Transmittal Number: R13514CP

CR 14312 tells you about:

  • Data reporting period and the phase-in of payment reductions
  • Mapping for new test codes
  • Updates for tests subject to the reasonable charge payment

Make sure your billing staff knows about Clinical Laboratory Fee Schedule (CLFS) changes and instructions effective January 1, 2026.

View the complete CMS Medicare Learning Network (MLN) Matters (MM)14312.

Last Updated Dec 11 , 2025