ASC Payment System: April 2026 Update

Number: 14445 
Release Date: April 7, 2026
Effective Date: April 1, 2026 
Implementation Date: April 6, 2026
Transmittal Number: R13704CP

CR 14445 tells you about:

  • New Hospital Outpatient Prospective Payment System (OPPS) device pass-through category payable in Ambulatory Surgical Centers (ASCs)
  • New HCPCS codes and payment status changes for:
  • ASC surgical procedures
    • Drugs, biologicals, and radiopharmaceuticals
    • Skin substitute products
    • Qualifying non-opioid treatments for pain relief

Make sure your billing staff knows about these ASC payment system updates, effective April 1, 2026.

View the complete CMS Medicare Learning Network (MLN) Matters (MM)14445.

Last Updated Apr 17 , 2026