ASC Payment System: October 2025 Update

Related CR Release Date: September 22, 2025
MLN Matters Number: MM14246
Effective Date: October 1, 2025 
Related Change Request (CR) Number: CR 14246
Implementation Date: October 6, 2025 
Related CR Transmittal Number: R13429CP

CR 14246 tells you about:

  • New Hospital Outpatient Prospective Payment System (OPPS) device pass-through category payable in Ambulatory Surgical Centers (ASCs) 
  • New HCPCS code describing the insertion of a pleural-peritoneal shunt with intercostal pump chamber
  • Drug, biological, and radiopharmaceutical coding updates
  • Skin substitute products

Make sure your billing staff knows about these payment system updates effective October 1, 2025.

View the complete CMS Medicare Learning Network (MLN) Matters (MM)14246.

Last Updated Nov 20 , 2025