ASC Payment System: October 2026 Update

Number: 14634
Release Date: October 8, 2026 
Effective Date: October 1, 2026 
Implementation Date: October 5, 2026 
Transmittal Number: R13983CP

CR 14634 tells you about:

  • ASC surgical procedures 
  • Drugs, biologicals, and radiopharmaceuticals 
  • Skin substitute products 
  • Non-opioid treatments for pain relief 

Make sure your billing staff knows about new HCPCS codes, revised code descriptors, and Ambulatory Surgical Center (ASC) payment indicator (PI) changes, effective October 1, 2026,

View the complete CMS Medicare Learning Network (MLN) Matters (MM)14634.

Last Updated Oct 22 , 2026