Multiple MolDX LCDs and Billing and Coding Articles Retirement - Effective January 22, 2026

Date Posted: January 22, 2026

The following Local Coverage Determinations (LCDs) and Billing and Coding Articles have been retired under contractor numbers: 02102 (AK), 02202 (ID), 02302 (OR), 02402 (WA), 03102 (AZ), 03202 (MT), 03302 (ND), 03402 (SD), 03502 (UT), and 03602 (WY).

Medicare Coverage Database Number LCD Title New Medicare Coverage Database Number
L36362 MolDX: Biomarkers in Cardiovascular Risk Assessment L36358
L38333 MolDX: Blood Product Molecular Antigen Typing L38331
L36386 MolDX: Breast Cancer Assay: Prosigna® L36380
L37824 MolDX: Breast Cancer Index® (BCI) Gene Expression Test L37822
L37072 MolDX: DecisionDx-UM (Uveal Melanoma) L37070
L37311 MolDX: EndoPredict® Breast Cancer Gene Expression Test L37295
L37891 MolDX: Envisia™, Veracyte™, Idiopathic Pulmonary Fibrosis Diagnostic Test L37887
L39688 MolDX: Gene Expression Profile Tests for Decision-Making in Castration Resistant and Metastatic Prostate Cancers L39686
L39946 MolDX: Genetic Testing for Heritable Thoracic Aortic Disease L39944
L36159 MolDX: Genetic Testing for Hypercoagulability / Thrombophilia (Factor V Leiden, Factor II Prothrombin, and MTHFR) L36155
L36544 MolDX: HLA-DQB1*06:02 Testing for Narcolepsy L36551
L37899 MolDX: Inivata™, InvisionFirst®, Liquid Biopsy for Patients with Lung Cancer L37897
L37748 MolDX: Melanoma Risk Stratification Molecular Testing L37750
L36192 MolDX: MGMT Promoter Methylation Analysis L36188
L39375 MolDX: Molecular Assays for the Diagnosis of Cutaneous Melanoma L39373
L39594 MolDX: Molecular Biomarker Testing for Risk Stratification of Cutaneous Squamous Cell Carcinoma L39589
L39469 MolDX: Molecular Biomarker Testing to Guide Targeted Therapy Selection in Rheumatoid Arthritis L39467
L39680 MolDX: Molecular Biomarkers for Risk Stratification of Indeterminate Pulmonary Nodules Following Bronchoscopy L39678
L39007 MolDX: Molecular Biomarkers to Risk-Stratify Patients at Increased Risk for Prostate Cancer L39005
L39264 MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasia L39262
Medicare Coverage Database Number Billing and Coding Article Title New Medicare Coverage Database Number
A57055 Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment A57037
A57376 Billing and Coding: MolDX: Blood Product Molecular Antigen Typing A57124
A57364 Billing and Coding: MolDX: Breast Cancer Assay: Prosigna® A57363
A57774 Billing and Coding: MolDX: Breast Cancer Index® (BCI) Gene Expression Test A57773
A57622 Billing and Coding: MolDX: DecisionDx-UM (Uveal Melanoma) A57621
A57608 Billing and Coding: MolDX: EndoPredict® Breast Cancer Gene Expression Test A57607
A57420 Billing and Coding: MolDX: Envisia™, Veracyte™, Idiopathic Pulmonary Fibrosis Diagnostic Test A57419
A59515 Billing and Coding: MolDX: Gene Expression Profile Tests for Decision-Making in Castration Resistant and Metastatic Prostate Cancers A59513
A59870 Billing and Coding: MolDX: Genetic Testing for Heritable Thoracic Aortic Disease A59868
A57424 Billing and Coding: MolDX: Genetic Testing for Hypercoagulability / Thrombophilia (Factor V Leiden, Factor II Prothrombin, and MTHFR) A57423
A57465 Billing and Coding: MolDX: HLA-DQB1*06:02 Testing for Narcolepsy A57441
A57665 Billing and Coding: MolDX: Inivata™, InvisionFirst®, Liquid Biopsy for Patients with Lung Cancer A57664
A57290 Billing and Coding: MolDX: Melanoma Risk Stratification Molecular Testing A57268
A57433 Billing and Coding: MolDX: MGMT Promoter Methylation Analysis A57432
A59181 Billing and Coding: MolDX: Molecular Assays for the Diagnosis of Cutaneous Melanoma A59179
A59401 Billing and Coding: MolDX: Molecular Biomarker Testing for Risk Stratification of Cutaneous Squamous Cell Carcinoma A59386
A59522 Billing and Coding: MolDX: Molecular Biomarker Testing to Guide Targeted Therapy Selection in Rheumatoid Arthritis A59521
A59507 Billing and Coding: MolDX: Molecular Biomarkers for Risk Stratification of Indeterminate Pulmonary Nodules Following Bronchoscopy A59505
A58724 Billing and Coding: MolDX: Molecular Biomarkers to Risk-Stratify Patients at Increased Risk for Prostate Cancer A58718
A59034 Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasia A59032

Effective Date: January 22, 2026

Rationale: The above-mentioned LCDs and Billing and Coding Articles were retired to consolidate JF policies with JE policies to have one unified document and policy number. Per the Centers for Medicare & Medicaid Services (CMS), this update is considered non-substantive and does not alter the intent of coverage or non-coverage outlined in any LCD.

Visit the Retired LCDs webpage to access the retired LCDs.

Last Updated Jan 22 , 2026